Found 14 matching trials
Naloxegol for Opioid-Related Gastroparesis
PHASE2The objective of this study is to evaluate the effects of naloxegol (a peri...
Location
Lewis Katz School of Medicine at Temple University
Open-label Study to Assess the Pharmacokinetics of NKTR-118 in Patients With Impaired Hepatic Function
PHASE1The purpose of this study is to assess the pharmacokinetics of NKTR-118 in ...
Study in Healthy Volunteers to Investigate the Effects of Quinidine on the Pharmacokinetics of NKTR-118
PHASE1Study in healthy volunteers to investigate the effects of Quinidine on the ...
Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
PHASE3The purpose of this study is to evaluate the long-term safety and tolerabil...
Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain
PHASE3The purpose of this study is to compare the effect of NKTR-118 with placebo...
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
PHASE3The purpose of this study is to evaluate the effect and safety of NKTR-118 ...
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation
PHASE3The purpose of this study is to evaluate the effect and safety of NKTR-118 ...
A Bioavailability Study With Alternate Methods of Administration of Naloxegol Tablets, and Solution
PHASE1This clinical study is an open-label, randomized, 4-period, 4-treatment, cr...
Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery
PHASE3Postoperative ileus, defined as the transient postoperative functional inhi...
Location
CMC Ambroise Paré
Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids
PHASE4This study evaluates the addition of naloxegol (Movantik) to a laxative pro...
Location
Tufts Medical Center